There are many ways to bind your book/comic/zine/manifesto, from perfect binding to tying it all together with rope to stuffing the loose pages in an envelope. I think, when planning a project, it's good to explore as many weird possibilities as you can before you just grab the stapler. I've been seeing this technique lately called the coptic stitch and I like it! It's a relatively simple way to achieve a cool handmade look. This PDF explains it well. And here's another site that tells you how to do it.